Melanotan 2 Acetate (MT-2)
Melanotan 2 is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), designed as a cyclic heptapeptide with altered receptor affinity. Due to these structural modifications, it may interact more broadly with melanocortin receptors and influence multiple biological processes beyond pigmentation, including appetite regulation and arousal.
Overview
Melanotan 2 is considered a non-selective agonist that may bind to several melanocortin receptor subtypes. Its effects depend on which receptor it activates:
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MC1R: Found in melanocytes, may stimulate melanin production, leading to darker skin pigmentation
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MC3R: Present in tissues like the brain, potentially involved in appetite regulation
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MC4R: Located in the central nervous system, possibly linked to sexual function and arousal
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MC5R: Distributed across various tissues, though its exact role is not fully understood
Interaction with MC1R may increase eumelanin production, contributing to skin darkening. Activation of MC4R, on the other hand, may influence neural pathways associated with libido and arousal.
Chemical Makeup
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Also known as: MT-II
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Molecular Formula: C50H69N15O9
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Molecular Weight: 1024.19 g/mol




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